Q. A 40 years old man presents to a hospital with the
history of headache, increased sweating, new onset snoring, and increase in hat
size. On further evaluation his IGF-1 and GH level are far above the normal
values. He undergoes MRI which shows mass in the pituitary. Physician makes the
diagnosis of acromegaly and advices patient to undergo surgery. Patient denies
surgery and wants some drugs for the problem. Which of the following drug will
the physician prefer to use for treating this condition?
A.
Bromocriptine
B.
Cabergoline
C.
Pegvisomant
D. Octreotide
Answer: See comment
Answer: See comment
Ans: D. Octreotide.
ReplyDeleteAll though all of the above mentioned drugs can be used for the treatment of acromegaly, somatostatin analogues are the preferred ones. You should always counsel about the one important side effect of somatostatin analogues i.e. cholestatis and gall stone formation.