Q. Which of the following is the most common complication of the bacterial   endocarditis?

     A. Glomerulonephritis
     B. Congestive heart failure
     C. Renal infarction and abscess
     D. Brain abscess
     E. Splenomegaly

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The correct answer is B. Congestive heart failure. Also, CHF is the most common cause of death in endocarditis. Before the antibiotic-era glomerulonephritis was a very common complication.

Q. Daptomycin should be avoided in

     A. Skin infections

     B. Soft tissue infections

     C. Right-sided endocarditis

     D. Pneumonia

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The correct answer is D. Pneumonia. Daptomycin is inactivated by the surfactant.

Q. Which of the following is the most likely diagnosis from this chest x-ray?
A. Transposition of great vessels
B. Hypoplastic left heart syndrome
C. Tetralogy of Fallot
D. Coarctation of aorta

Answer: See comment box

Q. Which of the following disease must be always ruled out in a patient with polyarteritis nodosa?
A. SLE
B. Hepatitis B
C. Hepatitis C
D. AIDS
E. Cryptococcal infection

Answer: See comment box.

   Q.       Which of the following test should be routinely performed in the patients started on statins?

A.      AST & ALT

B.      CPK

C.      Urea  & creatinine

D.      fT4  & TSH

Answer: See comment box.

Q. Which of the following is the most common neurological deficit of untreated bacterial meningitis?

A.     CN III  deficit

B.     CN VI deficit

C.     CN VII deficit

D.     CN VIII deficit

Answer: See comment box

Q. Which of the following cephalosporin will cover MRSA?
A. Cefazolin
B. Cefoxitin
C. Ceftriaxone
D. Cefepime
E. Ceftaroline

Ans: See comment

.    Q. Which of the following is the most sensitive test in the thyroid disease?

A.    TRH

B.     TSH

C.      Free T4

D.      Free T3

E.      TBG

Ans: See comment

   Q.     Varenicline should be avoided in patients with

A.      Myocardial infarction

B.      Depression

C.      Dilated cardiomyopathy

D.      Rheumatoid arthritis

Answer: See comment box

    Q. Which of the following drug is preferred as a prophylactic agent for the prevention of breast cancer in patients with a strong family history of breast cancer?

A.      Tamoxifen

B.      Raloxifene

C.      Trastuzumab

D.      Pertuzumab

Answer: See comment box

  Q.  A 40 years old man presents to a hospital with the history of headache, increased sweating, new onset  snoring, and increase in hat size. On further evaluation his IGF-1 and GH level are far above the normal values. He undergoes MRI which shows mass in the pituitary. Physician makes the diagnosis of acromegaly and advices patient to undergo surgery. Patient denies surgery and wants some drugs for the problem. Which of the following drug will the physician prefer to use for treating this condition?

A.      Bromocriptine

B.      Cabergoline

C.      Pegvisomant

D.   Octreotide

Answer: See comment